Moo Cow started in 1992 as a punk/hardcore fanzine in Burlington, VT. 1993 saw the advent of Moo Cow Records with the release of The Champions "Once and Future King" 7", a popular local band. Over the decades Moo Cow has released material by hardcore mainstays like Fall Silent, Disembodied, Despair, Overcast, Cave In, Earthmover, Morning Again, New Day Rising, Kieltolaki, The Ultimate Warriors, and many dozens of other bands from around the globe.

2018 saw the relocation of Moo Cow Records to Providence, RI and the first vinyl issue of Temperance's 1995 full length, "Searching for Silence", which was previously released only on CD and cassette.

Moo Cow released its first foray into the deathrock / goth punk scene with Nox Novacula's debut vinyl release in 2019, and in September 2019 it will be releasing Portland punk rockers, Death Ridge Boys, "Fooled Again" 7".